eGFR (CKD-EPI 2021)
Estimated glomerular filtration rate using the 2021 race-free CKD-EPI equation.
What is eGFR (CKD-EPI 2021)?
Estimated glomerular filtration rate using the 2021 race-free CKD-EPI equation. eGFR is intended for use in: Adults.
How to Use the eGFR Calculator
- Enter Serum creatinine in mg/dL.
- Enter Age in years.
- Enter Sex.
- Click Calculate to see your result and interpretation.
Formula & Version
This calculator uses formula version 1.0, last reviewed September 2026.
Clinical Considerations & Limitations
- Validated for adults ≥ 18 years with stable renal function — unreliable in acute kidney injury, pregnancy, extreme body size, or amputees.
- A serum-creatinine-based estimate — a cystatin-C-based or combined equation may be more accurate in some patients.
References
- Inker LA et al., N Engl J Med 2021;385:1737-1749 (2021 CKD-EPI Creatinine, race-free)
Frequently Asked Questions
What is eGFR (CKD-EPI 2021)?
Estimated glomerular filtration rate using the 2021 race-free CKD-EPI equation.
Who is eGFR intended for?
Adults. Always confirm applicability to your specific patient before use.
What are the limitations of eGFR?
Validated for adults ≥ 18 years with stable renal function — unreliable in acute kidney injury, pregnancy, extreme body size, or amputees. A serum-creatinine-based estimate — a cystatin-C-based or combined equation may be more accurate in some patients.
What formula or reference does eGFR use?
Inker LA et al., N Engl J Med 2021;385:1737-1749 (2021 CKD-EPI Creatinine, race-free)
Is eGFR a diagnosis?
No. eGFR produces a score or estimate to support clinical decision-making — it is not a diagnosis and should be interpreted alongside full clinical judgement.
