LDL Cholesterol (Friedewald)
Estimated LDL cholesterol from a standard lipid panel.
What is LDL Cholesterol (Friedewald)?
Estimated LDL cholesterol from a standard lipid panel. LDL Cholesterol is intended for use in: Adults.
How to Use the LDL Cholesterol Calculator
- Enter Total cholesterol in mg/dL.
- Enter HDL cholesterol in mg/dL.
- Enter Triglycerides in mg/dL.
- Click Calculate to see your result and interpretation.
Formula & Version
This calculator uses formula version 1.0, last reviewed September 2026.
Clinical Considerations & Limitations
- Not valid when triglycerides ≥ 400 mg/dL — a direct LDL measurement or the Martin/Hopkins formula should be used instead.
- Less accurate in the non-fasting state.
References
- Friedewald WT et al., Clin Chem 1972;18:499-502
Frequently Asked Questions
What is LDL Cholesterol (Friedewald)?
Estimated LDL cholesterol from a standard lipid panel.
Who is LDL Cholesterol intended for?
Adults. Always confirm applicability to your specific patient before use.
What are the limitations of LDL Cholesterol?
Not valid when triglycerides ≥ 400 mg/dL — a direct LDL measurement or the Martin/Hopkins formula should be used instead. Less accurate in the non-fasting state.
What formula or reference does LDL Cholesterol use?
Friedewald WT et al., Clin Chem 1972;18:499-502
Is LDL Cholesterol a diagnosis?
No. LDL Cholesterol produces a score or estimate to support clinical decision-making — it is not a diagnosis and should be interpreted alongside full clinical judgement.