Sodium Correction Rate (Adrogue-Madias)
Predicted change in serum sodium from IV fluid, to plan safe hyponatremia correction.
What is Sodium Correction Rate (Adrogue-Madias)?
Predicted change in serum sodium from IV fluid, to plan safe hyponatremia correction. Sodium Correction Rate is intended for use in: Adults.
How to Use the Sodium Correction Rate Calculator
- Enter Weight in kg.
- Enter Sex.
- Enter Current serum sodium in mEq/L.
- Enter Infusate sodium in mEq/L. e.g. 0.9% saline = 154, 3% saline = 513
- Enter Planned infusion rate in L/hr.
- Click Calculate to see your result and interpretation.
Formula & Version
This calculator uses formula version 1.0, last reviewed September 2026.
Clinical Considerations & Limitations
- Assumes no ongoing fluid losses and a fixed total body water — actual response can differ, especially in ongoing diuresis (e.g. from desmopressin-limited correction).
- Guideline-recommended correction limits are typically ≤ 8 (some say ≤ 10) mEq/L per 24 hours to reduce osmotic demyelination risk — this tool does not enforce that limit for you.
- Uses standard adult total-body-water fractions (0.6 male / 0.5 female) — less accurate in the elderly or in edematous states.
References
- Adrogué HJ, Madias NE, N Engl J Med 2000;342:1581-1589
Frequently Asked Questions
What is Sodium Correction Rate (Adrogue-Madias)?
Predicted change in serum sodium from IV fluid, to plan safe hyponatremia correction.
Who is Sodium Correction Rate intended for?
Adults. Always confirm applicability to your specific patient before use.
What are the limitations of Sodium Correction Rate?
Assumes no ongoing fluid losses and a fixed total body water — actual response can differ, especially in ongoing diuresis (e.g. from desmopressin-limited correction). Guideline-recommended correction limits are typically ≤ 8 (some say ≤ 10) mEq/L per 24 hours to reduce osmotic demyelination risk — this tool does not enforce that limit for you. Uses standard adult total-body-water fractions (0.6 male / 0.5 female) — less accurate in the elderly or in edematous states.
What formula or reference does Sodium Correction Rate use?
Adrogué HJ, Madias NE, N Engl J Med 2000;342:1581-1589
Is Sodium Correction Rate a diagnosis?
No. Sodium Correction Rate produces a score or estimate to support clinical decision-making — it is not a diagnosis and should be interpreted alongside full clinical judgement.
