FIB-4 Index
Non-invasive liver fibrosis risk estimate.
RESULT
FIB-4 Index
What is FIB-4 Index?
Non-invasive liver fibrosis risk estimate. FIB-4 Index is intended for use in: Adults.
How to Use the FIB-4 Index Calculator
- Enter Age in years.
- Enter AST in U/L.
- Enter ALT in U/L.
- Enter Platelet count in ×10⁹/L.
- Click Calculate to see your result and interpretation.
Formula & Version
This calculator uses formula version 1.0, last reviewed September 2026.
Clinical Considerations & Limitations
- Standard cut-offs (1.45 / 3.25) were derived in HIV/HCV co-infected patients ≤ 65 years — a higher lower cut-off (≈2.0) is sometimes used in patients over 65 to reduce false positives.
References
- Sterling RK et al., Hepatology 2006;43:1317-1325
Frequently Asked Questions
What is FIB-4 Index?
Non-invasive liver fibrosis risk estimate.
Who is FIB-4 Index intended for?
Adults. Always confirm applicability to your specific patient before use.
What are the limitations of FIB-4 Index?
Standard cut-offs (1.45 / 3.25) were derived in HIV/HCV co-infected patients ≤ 65 years — a higher lower cut-off (≈2.0) is sometimes used in patients over 65 to reduce false positives.
What formula or reference does FIB-4 Index use?
Sterling RK et al., Hepatology 2006;43:1317-1325
Is FIB-4 Index a diagnosis?
No. FIB-4 Index produces a score or estimate to support clinical decision-making — it is not a diagnosis and should be interpreted alongside full clinical judgement.
Medical Disclaimer: Medical calculators are provided for informational and educational purposes only. Results should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always verify results with a qualified healthcare professional.
