Maddrey's Discriminant Function
Severity of alcoholic hepatitis.
RESULT
Maddrey's Discriminant Function
What is Maddrey's Discriminant Function?
Severity of alcoholic hepatitis. Maddrey's Discriminant Function is intended for use in: Adults.
How to Use the Maddrey's Discriminant Function Calculator
- Enter Patient prothrombin time (PT) in sec.
- Enter Control (lab) PT in sec.
- Enter Total bilirubin in mg/dL.
- Click Calculate to see your result and interpretation.
Formula & Version
This calculator uses formula version 1.0, last reviewed September 2026.
Clinical Considerations & Limitations
- The MELD score is increasingly used alongside or instead of Maddrey's DF for treatment decisions in alcoholic hepatitis.
References
- Maddrey WC et al., Gastroenterology 1978;75:193-199
Frequently Asked Questions
What is Maddrey's Discriminant Function?
Severity of alcoholic hepatitis.
Who is Maddrey's Discriminant Function intended for?
Adults. Always confirm applicability to your specific patient before use.
What are the limitations of Maddrey's Discriminant Function?
The MELD score is increasingly used alongside or instead of Maddrey's DF for treatment decisions in alcoholic hepatitis.
What formula or reference does Maddrey's Discriminant Function use?
Maddrey WC et al., Gastroenterology 1978;75:193-199
Is Maddrey's Discriminant Function a diagnosis?
No. Maddrey's Discriminant Function produces a score or estimate to support clinical decision-making — it is not a diagnosis and should be interpreted alongside full clinical judgement.
Medical Disclaimer: Medical calculators are provided for informational and educational purposes only. Results should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always verify results with a qualified healthcare professional.
